Retinitis Pigmentosa Mutants Provide Insight into the Role of the N-terminal Cap in Rhodopsin Folding, Structure, and Function

Por Opefi, Chikwado A., South, Kieron, Reynolds, Christopher A., Smith, Steven O., Reeves, Philip J.
Publicado em 2013

Free backbone carbonyls mediate rhodopsin activation

Por Kimata, Naoki, Pope, Andreyah, Sanchez-Reyes, Omar B., Eilers, Markus, Opefi, Chikwado A., Ziliox, Martine, Reeves, Philip J., Smith, Steven O.
Publicado no Nat Struct Mol Biol (2016)

Highly conserved tyrosine stabilizes the active state of rhodopsin

Por Goncalves, Joseph A., South, Kieron, Ahuja, Shivani, Zaitseva, Ekaterina, Opefi, Chikwado A., Eilers, Markus, Vogel, Reiner, Reeves, Philip J., Smith, Steven O.
Publicado em 2010

Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

Por Kimata, Naoki, Pope, Andreyah, Eilers, Markus, Opefi, Chikwado A., Ziliox, Martine, Hirshfeld, Amiram, Zaitseva, Ekaterina, Vogel, Reiner, Sheves, Mordechai, Reeves, Philip J., Smith, Steven O.
Publicado no Nat Commun (2016)

Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

Por Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A., South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M., Kanuga, Naheed, Mackenzie, Francesca E., Dubis, Adam M., Georgiadis, Anastasios, Graca, Anna B., Pearson, Rachael A., Ali, Robin R., Sakami, Sanae, Palczewski, Krzysztof, Sherman, Michael Y., Reeves, Philip J., Cheetham, Michael E.
Publicado no Hum Mol Genet (2017)