Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration

Autor Ovando-Roche, Patrick, Georgiadis, Anastasios, Smith, Alexander J., Pearson, Rachael A., Ali, Robin R.
Vydáno v Curr Stem Cell Rep (2017)

Regulation of PCNA and Cyclin D1 Expression and Epithelial Morphogenesis by the ZO-1-Regulated Transcription Factor ZONAB/DbpA

Autor Sourisseau, Tony, Georgiadis, Anastasios, Tsapara, Anna, Ali, Robin R., Pestell, Richard, Matter, Karl, Balda, Maria S.
Vydáno 2006

The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice

Autor Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W. B., Balaggan, Kamaljit S., Mowat, Freya, West, Emma L., Munro, Peter M. G., Thrasher, Adrian J., Matter, Karl, Balda, Maria S., Ali, Robin R.
Vydáno 2010

Use of bioreactors for culturing human retinal organoids improves photoreceptor yields

Autor Ovando-Roche, Patrick, West, Emma L., Branch, Matthew J., Sampson, Robert D., Fernando, Milan, Munro, Peter, Georgiadis, Anastasios, Rizzi, Matteo, Kloc, Magdalena, Naeem, Arifa, Ribeiro, Joana, Smith, Alexander J., Gonzalez-Cordero, Anai, Ali, Robin R.
Vydáno v Stem Cell Res Ther (2018)

Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development

Autor Lange, Clemens A. K., Luhmann, Ulrich F. O., Mowat, Freya M., Georgiadis, Anastasios, West, Emma L., Abrahams, Sabu, Sayed, Haroon, Powner, Michael B., Fruttiger, Marcus, Smith, Alexander J., Sowden, Jane C., Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W. B.
Vydáno 2012

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

Autor Gonzalez-Cordero, Anai, West, Emma L., Pearson, Rachael A., Duran, Yanai, Carvalho, Livia S., Chu, Colin J., Naeem, Arifa, Blackford, Samuel J. I., Georgiadis, Anastasios, Lakowski, Jorn, Hubank, Mike, Smith, Alexander J., Bainbridge, James W. B., Sowden, Jane C., Ali, Robin R.
Vydáno 2013

Prevention of Photoreceptor Cell Loss in a Cln6(nclf) Mouse Model of Batten Disease Requires CLN6 Gene Transfer to Bipolar Cells

Autor kleine Holthaus, Sophia-Martha, Ribeiro, Joana, Abelleira-Hervas, Laura, Pearson, Rachael A., Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Rizzi, Matteo, Hoke, Justin, Maswood, Ryea, Azam, Selina, Luhmann, Ulrich F.O., Smith, Alexander J., Mole, Sara E., Ali, Robin R.
Vydáno v Mol Ther (2018)

Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration

Autor Kruczek, Kamil, Gonzalez-Cordero, Anai, Goh, Debbie, Naeem, Arifa, Jonikas, Mindaugas, Blackford, Samuel J.I., Kloc, Magdalena, Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Maswood, Ryea N., Smith, Alexander J., Decembrini, Sarah, Arsenijevic, Yvan, Sowden, Jane C., Pearson, Rachael A., West, Emma L., Ali, Robin R.
Vydáno v Stem Cell Reports (2017)

Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

Autor Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A., South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M., Kanuga, Naheed, Mackenzie, Francesca E., Dubis, Adam M., Georgiadis, Anastasios, Graca, Anna B., Pearson, Rachael A., Ali, Robin R., Sakami, Sanae, Palczewski, Krzysztof, Sherman, Michael Y., Reeves, Philip J., Cheetham, Michael E.
Vydáno v Hum Mol Genet (2017)