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Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development

Molecular oxygen is essential for the development, growth and survival of multicellular organisms. Hypoxic microenvironments and oxygen gradients are generated physiologically during embryogenesis and organogenesis. In the eye, oxygen plays a crucial role in both physiological vascular development a...

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Bibliographic Details
Main Authors: Lange, Clemens A. K., Luhmann, Ulrich F. O., Mowat, Freya M., Georgiadis, Anastasios, West, Emma L., Abrahams, Sabu, Sayed, Haroon, Powner, Michael B., Fruttiger, Marcus, Smith, Alexander J., Sowden, Jane C., Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W. B.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367444/
https://ncbi.nlm.nih.gov/pubmed/22627278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.070813
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