Development of Stem Cell Therapies for Retinal Degeneration

Tekijä West, Emma L., Ribeiro, Joana, Ali, Robin R.
Julkaisussa Cold Spring Harb Perspect Biol (2020)

Müller Glia Activation in Response to Inherited Retinal Degeneration Is Highly Varied and Disease-Specific

Tekijä Hippert, Claire, Graca, Anna B., Barber, Amanda C., West, Emma L., Smith, Alexander J., Ali, Robin R., Pearson, Rachael A.
Julkaisussa PLoS One (2015)

Dominant Cone-Rod Dystrophy: A Mouse Model Generated by Gene Targeting of the GCAP1/Guca1a Gene

Tekijä Buch, Prateek K., Mihelec, Marija, Cottrill, Phillippa, Wilkie, Susan E., Pearson, Rachael A., Duran, Yanai, West, Emma L., Michaelides, Michel, Ali, Robin R., Hunt, David M.
Julkaistu 2011

The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice

Tekijä Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W. B., Balaggan, Kamaljit S., Mowat, Freya, West, Emma L., Munro, Peter M. G., Thrasher, Adrian J., Matter, Karl, Balda, Maria S., Ali, Robin R.
Julkaistu 2010

Long-Term Survival of Photoreceptors Transplanted into the Adult Murine Neural Retina Requires Immune Modulation

Tekijä West, Emma L., Pearson, Rachael A., Barker, Susie E., Luhmann, Ulrich F. O., Maclaren, Robert E., Barber, Amanda C., Duran, Yanai, Smith, Alexander J., Sowden, Jane C., Ali, Robin R.
Julkaistu 2010

Repair of the degenerate retina by photoreceptor transplantation

Tekijä Barber, Amanda C., Hippert, Claire, Duran, Yanai, West, Emma L., Bainbridge, James W. B., Warre-Cornish, Katherine, Luhmann, Ulrich F. O., Lakowski, Jorn, Sowden, Jane C., Ali, Robin R., Pearson, Rachael A.
Julkaistu 2013

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell‐Derived Self‐Forming Retina

Tekijä Lakowski, Jorn, Gonzalez‐Cordero, Anai, West, Emma L., Han, Ya‐Ting, Welby, Emily, Naeem, Arifa, Blackford, Samuel J. I., Bainbridge, James W. B., Pearson, Rachael A., Ali, Robin R., Sowden, Jane C.
Julkaisussa Stem Cells (2015)

Use of bioreactors for culturing human retinal organoids improves photoreceptor yields

Tekijä Ovando-Roche, Patrick, West, Emma L., Branch, Matthew J., Sampson, Robert D., Fernando, Milan, Munro, Peter, Georgiadis, Anastasios, Rizzi, Matteo, Kloc, Magdalena, Naeem, Arifa, Ribeiro, Joana, Smith, Alexander J., Gonzalez-Cordero, Anai, Ali, Robin R.
Julkaisussa Stem Cell Res Ther (2018)

RPGR isoform imbalance causes ciliary defects due to exon ORF15 mutations in X-linked retinitis pigmentosa (XLRP)

Tekijä Moreno-Leon, Laura, West, Emma L, O’Hara-Wright, Michelle, Li, Linjing, Nair, Rohini, He, Jie, Anand, Manisha, Sahu, Bhubanananda, Chavali, Venkat Ramana Murthy, Smith, Alexander J, Ali, Robin R, Jacobson, Samuel G, Cideciyan, Artur V, Khanna, Hemant
Julkaisussa Hum Mol Genet (2020)

Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development

Tekijä Lange, Clemens A. K., Luhmann, Ulrich F. O., Mowat, Freya M., Georgiadis, Anastasios, West, Emma L., Abrahams, Sabu, Sayed, Haroon, Powner, Michael B., Fruttiger, Marcus, Smith, Alexander J., Sowden, Jane C., Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W. B.
Julkaistu 2012

Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

Tekijä Gonzalez-Cordero, Anai, West, Emma L., Pearson, Rachael A., Duran, Yanai, Carvalho, Livia S., Chu, Colin J., Naeem, Arifa, Blackford, Samuel J. I., Georgiadis, Anastasios, Lakowski, Jorn, Hubank, Mike, Smith, Alexander J., Bainbridge, James W. B., Sowden, Jane C., Ali, Robin R.
Julkaistu 2013

Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration

Tekijä Kruczek, Kamil, Gonzalez-Cordero, Anai, Goh, Debbie, Naeem, Arifa, Jonikas, Mindaugas, Blackford, Samuel J.I., Kloc, Magdalena, Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Maswood, Ryea N., Smith, Alexander J., Decembrini, Sarah, Arsenijevic, Yvan, Sowden, Jane C., Pearson, Rachael A., West, Emma L., Ali, Robin R.
Julkaisussa Stem Cell Reports (2017)

Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors

Tekijä Ribeiro, Joana, Procyk, Christopher A., West, Emma L., O’Hara-Wright, Michelle, Martins, Monica F., Khorasani, Majid Moshtagh, Hare, Aura, Basche, Mark, Fernando, Milan, Goh, Debbie, Jumbo, Neeraj, Rizzi, Matteo, Powell, Kate, Tariq, Menahil, Michaelides, Michel, Bainbridge, James W.B., Smith, Alexander J., Pearson, Rachael A., Gonzalez-Cordero, Anai, Ali, Robin R.
Julkaisussa Cell Rep (2021)

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors

Tekijä Gonzalez-Cordero, Anai, Kruczek, Kamil, Naeem, Arifa, Fernando, Milan, Kloc, Magdalena, Ribeiro, Joana, Goh, Debbie, Duran, Yanai, Blackford, Samuel J.I., Abelleira-Hervas, Laura, Sampson, Robert D., Shum, Ian O., Branch, Matthew J., Gardner, Peter J., Sowden, Jane C., Bainbridge, James W.B., Smith, Alexander J., West, Emma L., Pearson, Rachael A., Ali, Robin R.
Julkaisussa Stem Cell Reports (2017)