Gene therapy for neovascular age-related macular degeneration: rationale, clinical trials and future directions

od de Guimaraes, Thales Antonio Cabral, Georgiou, Michalis, Bainbridge, James W B, Michaelides, Michel
Izdano u Br J Ophthalmol (2021)

Severe Loss of Tritan Color Discrimination in RPE65 Associated Leber Congenital Amaurosis

od Kumaran, Neruban, Ripamonti, Caterina, Kalitzeos, Angelos, Rubin, Gary S., Bainbridge, James W. B., Michaelides, Michel
Izdano u Invest Ophthalmol Vis Sci (2018)

Validation of a Vision-Guided Mobility Assessment for RPE65-Associated Retinal Dystrophy

od Kumaran, Neruban, Ali, Robin R., Tyler, Nick A., Bainbridge, James W. B., Michaelides, Michel, Rubin, Gary S.
Izdano u Transl Vis Sci Technol (2020)

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65-Associated Leber Congenital Amaurosis

od Kumaran, Neruban, Rubin, Gary S., Kalitzeos, Angelos, Fujinami, Kaoru, Bainbridge, James W. B., Weleber, Richard G., Michaelides, Michel
Izdano u Invest Ophthalmol Vis Sci (2018)

Long-Term Preservation of Cones and Improvement in Visual Function Following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis Caused by Guanylate Cyclase-1 Deficiency

od Mihelec, Marija, Pearson, Rachael A., Robbie, Scott J., Buch, Prateek K., Azam, Selina A., Bainbridge, James W.B., Smith, Alexander J., Ali, Robin R.
Izdano 2011

Assessment and In Vivo Scoring of Murine Experimental Autoimmune Uveoretinitis Using Optical Coherence Tomography

od Chu, Colin J., Herrmann, Philipp, Carvalho, Livia S., Liyanage, Sidath E., Bainbridge, James W. B., Ali, Robin R., Dick, Andrew D., Luhmann, Ulrich F. O.
Izdano 2013

Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization

od Villacampa, Pilar, Menger, Katja E., Abelleira, Laura, Ribeiro, Joana, Duran, Yanai, Smith, Alexander J., Ali, Robin R., Luhmann, Ulrich F., Bainbridge, James W. B.
Izdano u PLoS One (2017)

Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration

od Luhmann, Ulrich F.O., Carvalho, Livia S., Robbie, Scott J., Cowing, Jill A., Duran, Yanai, Munro, Peter M.G., Bainbridge, James W.B., Ali, Robin R.
Izdano 2013

Endogenous Erythropoietin Protects Neuroretinal Function in Ischemic Retinopathy

od Mowat, Freya M., Gonzalez, Francisco, Luhmann, Ulrich F.O., Lange, Clemens A., Duran, Yanai, Smith, Alexander J., Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W.B.
Izdano 2012

Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell‐Derived Retinal Organoids and Fetal Retinae

od Lakowski, Jörn, Welby, Emily, Budinger, Dimitri, Di Marco, Fabiana, Di Foggia, Valentina, Bainbridge, James W.B., Wallace, Kyle, Gamm, David M., Ali, Robin R., Sowden, Jane C.
Izdano u Stem Cells (2018)

Facedown Positioning Following Surgery for Large Full-Thickness Macular Hole: A Multicenter Randomized Clinical Trial

od Pasu, Saruban, Bell, Lauren, Zenasni, Zohra, Lanz, Doris, Simmonds, Irene A, Thompson, Ann, Yorston, David, Laidlaw, D. Alistair H., Bunce, Catey, Hooper, Richard, Bainbridge, James W. B.
Izdano u JAMA Ophthalmol (2020)

Retinal Structure in RPE65-Associated Retinal Dystrophy

od Kumaran, Neruban, Georgiou, Michalis, Bainbridge, James W. B., Bertelsen, Mette, Larsen, Michael, Blanco-Kelly, Fiona, Ayuso, Carmen, Tran, Hoai Viet, Munier, Francis L., Kalitzeos, Angelos, Michaelides, Michel
Izdano u Invest Ophthalmol Vis Sci (2020)

HIF-1alpha and HIF-2alpha Are Differentially Activated in Distinct Cell Populations in Retinal Ischaemia

od Mowat, Freya M., Luhmann, Ulrich F. O., Smith, Alexander J., Lange, Clemens, Duran, Yanai, Harten, Sarah, Shukla, Deepa, Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W. B.
Izdano 2010

The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice

od Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W. B., Balaggan, Kamaljit S., Mowat, Freya, West, Emma L., Munro, Peter M. G., Thrasher, Adrian J., Matter, Karl, Balda, Maria S., Ali, Robin R.
Izdano 2010

Intravitreal Pharmacokinetic Study of the Antiangiogenic Glycoprotein Opticin

od del Amo, Eva M., Griffiths, John R., Klaska, Izabela P., Hoke, Justin, White, Anne, Aarons, Leon, Cooper, Garth J. S., Bainbridge, James W. B., Bishop, Paul N., Unwin, Richard D.
Izdano u Mol Pharm (2020)

The drusen-like phenotype in aging Ccl2 knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages

od Luhmann, Ulrich F.O., Robbie, Scott, Munro, Peter M.G., Barker, Susie E., Duran, Yanai, Luong, Vy, Fitzke, Frederick W., Bainbridge, James W.B., Ali, Robin R., MacLaren, Robert E.
Izdano 2009

Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice

od Barker, Susie E, Broderick, Cathryn A, Robbie, Scott J, Duran, Yanai, Natkunarajah, Mythili, Buch, Prateek, Balaggan, Kamaljit S, MacLaren, Robert E, Bainbridge, James W B, Smith, Alexander J, Ali, Robin R
Izdano 2009

Repair of the degenerate retina by photoreceptor transplantation

od Barber, Amanda C., Hippert, Claire, Duran, Yanai, West, Emma L., Bainbridge, James W. B., Warre-Cornish, Katherine, Luhmann, Ulrich F. O., Lakowski, Jorn, Sowden, Jane C., Ali, Robin R., Pearson, Rachael A.
Izdano 2013

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell‐Derived Self‐Forming Retina

od Lakowski, Jorn, Gonzalez‐Cordero, Anai, West, Emma L., Han, Ya‐Ting, Welby, Emily, Naeem, Arifa, Blackford, Samuel J. I., Bainbridge, James W. B., Pearson, Rachael A., Ali, Robin R., Sowden, Jane C.
Izdano u Stem Cells (2015)

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179

od Nishiguchi, Koji M., Carvalho, Livia S., Rizzi, Matteo, Powell, Kate, Holthaus, Sophia-Martha kleine, Azam, Selina A., Duran, Yanai, Ribeiro, Joana, Luhmann, Ulrich F. O., Bainbridge, James W. B., Smith, Alexander J., Ali, Robin R.
Izdano u Nat Commun (2015)