A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65-Associated Leber Congenital Amaurosis

PURPOSE: RPE65-associated Leber congenital amaurosis (RPE65-LCA) is an early-onset severe retinal dystrophy associated with progressive visual field loss. Phase I/II and III gene therapy trials have identified improved retinal sensitivity but little is known about the natural history of retinal sens...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kumaran, Neruban, Rubin, Gary S., Kalitzeos, Angelos, Fujinami, Kaoru, Bainbridge, James W. B., Weleber, Richard G., Michaelides, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Clinical and Epidemiologic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040235/
https://ncbi.nlm.nih.gov/pubmed/30025081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-23873
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