Regulation of PCNA and Cyclin D1 Expression and Epithelial Morphogenesis by the ZO-1-Regulated Transcription Factor ZONAB/DbpA

The tight junction protein ZO-1 inhibits G(1)/S-phase transition by cytoplasmic sequestration of a complex formed by CDK4 and the transcription factor ZONAB. Canine ZONAB is the homologue of human DbpA, an E2F target gene that is overexpressed in different carcinomas. Since the ZONAB target genes th...

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Hlavní autoři: Sourisseau, Tony, Georgiadis, Anastasios, Tsapara, Anna, Ali, Robin R., Pestell, Richard, Matter, Karl, Balda, Maria S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430269/
https://ncbi.nlm.nih.gov/pubmed/16508013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2387-2398.2006
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