Helix Movement is Coupled to Displacement of the Second Extracellular Loop in Rhodopsin Activation

The second extracellular loop (EL2) of rhodopsin forms a cap over the binding site of its photoreactive 11-cis retinylidene chromophore. A critical question has been whether EL2 forms a reversible gate that opens upon activation or acts as a rigid barrier. Distance measurements using solid-state (13...

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Detalhes bibliográficos
Main Authors: Ahuja, Shivani, Hornak, Viktor, Yan, Elsa C. Y., Syrett, Natalie, Goncalves, Joseph A., Hirshfeld, Amiram, Ziliox, Martine, Sakmar, Thomas P., Sheves, Mordechai, Reeves, Philip J., Smith, Steven O., Eilers, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705779/
https://ncbi.nlm.nih.gov/pubmed/19182802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1549
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