Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints

Structural restraints provided by solid-state NMR measurements of the metarhodopsin II intermediate are combined with molecular dynamics simulations to help visualize the structural changes in the light activation of rhodopsin. Since the time scale for the formation of the metarhodopsin II intermedi...

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Main Authors: Hornak, Viktor, Ahuja, Shivani, Eilers, Markus, Goncalves, Joseph A., Sheves, Mordechai, Reeves, Philip J., Smith, Steven O.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822010/
https://ncbi.nlm.nih.gov/pubmed/20004206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.003
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