Light activation of rhodopsin: insights from molecular dynamics simulations guided by solid-state NMR distance restraints

Structural restraints provided by solid-state NMR measurements of the metarhodopsin II intermediate are combined with molecular dynamics simulations to help visualize the structural changes in the light activation of rhodopsin. Since the time scale for the formation of the metarhodopsin II intermedi...

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Bibliographic Details
Main Authors: Hornak, Viktor, Ahuja, Shivani, Eilers, Markus, Goncalves, Joseph A., Sheves, Mordechai, Reeves, Philip J., Smith, Steven O.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822010/
https://ncbi.nlm.nih.gov/pubmed/20004206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.003
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