Caricamento...
Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth
EphA2 receptor kinase could become a novel target for anti-glioblastoma treatment. Doxazosin previously identified acts like the endogenous ligand of EphA2 and induces cell apoptosis. Through lead structure modification a derivative of Doxazosin possessing unique dimeric structure showed an improvem...
Salvato in:
| Pubblicato in: | Bioorg Med Chem |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7446891/ https://ncbi.nlm.nih.gov/pubmed/32828423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115656 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|