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Design and Synthesis of Small Molecule Agonists of EphA2 Receptor
Ligand-independent activation of EphA2 receptor kinase promotes cancer metastasis and invasion. Activating EphA2 receptor tyrosine kinase with small molecule agonist is a novel strategy to treat EphA2 overexpressing cancer. In this study, we performed a lead optimization of a small molecule Doxazosi...
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| Publicado no: | Eur J Med Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752149/ https://ncbi.nlm.nih.gov/pubmed/29128116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.10.026 |
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