Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors

The erythropoietin-producing hepatocellular (Eph) family of receptor tyrosine kinases regulates a multitude of physiological and pathological processes. Despite the numerous possible research and therapeutic applications of agents capable of modulating Eph receptor function, no small molecule inhibi...

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Detalhes bibliográficos
Main Authors: Noberini, Roberta, Koolpe, Mitchell, Peddibhotla, Satyamaheshwar, Dahl, Russell, Su, Ying, Cosford, Nicholas D. P., Roth, Gregory P., Pasquale, Elena B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570887/
https://ncbi.nlm.nih.gov/pubmed/18728010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804103200
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