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Synthesis and biological evaluation of selective tubulin inhibitors as anti-trypanosomal agents
African trypanosomiasis is still a threat to human health due to the severe side-effects of current drugs. We identified selective tubulin inhibitors that showed the promise to the treatment of this disease, which was based on the tubulin protein structural difference between mammalian and trypanoso...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509440/ https://ncbi.nlm.nih.gov/pubmed/28428042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.04.009 |
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