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Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents

OBJECTIVES: There is an urgent need to develop a safe, effective, orally active, and inexpensive therapy for African trypanosomiasis due to the drawbacks of current drugs. Selective tubulin inhibitors have the potential to be promising drug candidates for the treatment of this disease, which is base...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nanavaty, Vishal, Lama, Rati, Sandhu, Ranjodh, Zhong, Bo, Kulman, Daniel, Bobba, Viharika, Zhao, Anran, Li, Bibo, Su, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714897/
https://ncbi.nlm.nih.gov/pubmed/26771307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146289
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