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Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents

OBJECTIVES: There is an urgent need to develop a safe, effective, orally active, and inexpensive therapy for African trypanosomiasis due to the drawbacks of current drugs. Selective tubulin inhibitors have the potential to be promising drug candidates for the treatment of this disease, which is base...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Nanavaty, Vishal, Lama, Rati, Sandhu, Ranjodh, Zhong, Bo, Kulman, Daniel, Bobba, Viharika, Zhao, Anran, Li, Bibo, Su, Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714897/
https://ncbi.nlm.nih.gov/pubmed/26771307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146289
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