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Lead optimization of dual tubulin and Hsp27 inhibitors
Tubulin and heat shock protein 27 (Hsp27) are well-characterized molecular targets for anti-cancer drug development. We previously identified lead compounds that inhibited both Hsp27 and tubulin. These compounds exhibited extensive anti-cancer activities against the proliferation of various human ca...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057015/ https://ncbi.nlm.nih.gov/pubmed/24780601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.04.038 |
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