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Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors
[Image: see text] Heat shock protein 27 (Hsp27) is a chaperone protein, and its expression is increased in response to various stress stimuli including anticancer chemotherapy, which allows the cells to survive and causes drug resistance. We previously identified lead compounds that bound to Hsp27 a...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855081/ https://ncbi.nlm.nih.gov/pubmed/23767669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4004736 |
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