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Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors
[Image: see text] Heat shock protein 27 (Hsp27) is a chaperone protein, and its expression is increased in response to various stress stimuli including anticancer chemotherapy, which allows the cells to survive and causes drug resistance. We previously identified lead compounds that bound to Hsp27 a...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855081/ https://ncbi.nlm.nih.gov/pubmed/23767669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4004736 |
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