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EphA2 Receptor Unliganded Dimers Suppress EphA2 Pro-tumorigenic Signaling
The EphA2 receptor tyrosine kinase promotes cell migration and cancer malignancy through a ligand- and kinase-independent distinctive mechanism that has been linked to high Ser-897 phosphorylation and low tyrosine phosphorylation. Here, we demonstrate that EphA2 forms dimers in the plasma membrane o...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646390/ https://ncbi.nlm.nih.gov/pubmed/26363067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676866 |
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