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A Small Peptide Promotes EphA2 Kinase-Dependent Signaling by Stabilizing EphA2 Dimers

BACKGROUND: The EphA2 receptor tyrosine kinase is known to promote cancer cell malignancy in the absence of activation by ephrin ligands. This behavior depends on high EphA2 phosphorylation on Ser897 and low tyrosine phosphorylation, resulting in increased cell migration and invasiveness. We have pr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biochim Biophys Acta
Päätekijät: Singh, Deo R., Pasquale, Elena B., Hristova, Kalina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950921/
https://ncbi.nlm.nih.gov/pubmed/27281300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.06.004
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