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Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling
The EPH receptor A2 (EphA2) tyrosine kinase plays an important role in a plethora of biological and disease processes, ranging from angiogenesis and cancer to inflammation and parasitic infections. EphA2 is therefore considered an important drug target. Two short peptides previously identified by ph...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552433/ https://ncbi.nlm.nih.gov/pubmed/31015204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008213 |
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