Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in Glioblastoma

Androgen receptor (AR) contributes to the progression of glioblastoma (GBM), and antiandrogen agents have the potential to be used for the treatment of GBM. However, AR mutation commonly happens in GBM, which makes the antiandrogen agents less effective. Heat shock 27 kDa protein (HSP27) is a well-d...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Med Chem
Asıl Yazarlar: Li, Yaxin, Orahoske, Cody M., Geldenhuys, Werner J., Bhattarai, Asmita, Sabbagh, Abboud, Bobba, Viharika, Salem, Fatma M., Zhang, Wenjing, Shukla, Girish C., Lathia, Justin D., Wang, Bingcheng, Su, Bin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284899/
https://ncbi.nlm.nih.gov/pubmed/33523674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01537
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller