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Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in Glioblastoma
Androgen receptor (AR) contributes to the progression of glioblastoma (GBM), and antiandrogen agents have the potential to be used for the treatment of GBM. However, AR mutation commonly happens in GBM, which makes the antiandrogen agents less effective. Heat shock 27 kDa protein (HSP27) is a well-d...
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| Publicado no: | J Med Chem |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284899/ https://ncbi.nlm.nih.gov/pubmed/33523674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01537 |
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