Targeting cPLA(2) derived lipid hydroperoxides as a potential intervention for sarcopenia

Defects in neuromuscular innervation contribute significantly to the age-related decline in muscle mass and function (sarcopenia). Our previous studies demonstrated that denervation induces muscle mitochondrial hydroperoxide production (H(2)O(2) and lipid hydroperoxides (LOOHs)). Here we define the...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Pharaoh, Gavin, Brown, Jacob L., Sataranatarajan, Kavithalakshmi, Kneis, Parker, Bian, Jan, Ranjit, Rojina, Hadad, Niran, Georgescu, Constantin, Rabinovitch, Peter, Ran, Qitao, Wren, Jonathan D., Freeman, Willard, Kinter, Michael, Richardson, Arlan, Van Remmen, Holly
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435184/
https://ncbi.nlm.nih.gov/pubmed/32811851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70792-7
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