Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice

Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of dietary interventions shows promise for metabo...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Pharaoh, Gavin, Sataranatarajan, Kavithalakshmi, Street, Kaitlyn, Hill, Shauna, Gregston, Jake, Ahn, Bumsoo, Kinter, Caroline, Kinter, Michael, Van Remmen, Holly
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554287/
https://ncbi.nlm.nih.gov/pubmed/31213966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00487
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