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Metabolic and Stress Response Changes Precede Disease Onset in the Spinal Cord of Mutant SOD1 ALS Mice

Many Amyotrophic Lateral Sclerosis (ALS) patients experience hypermetabolism, or an increase in measured vs. calculated metabolic rate. The cause of hypermetabolism and the effects on neuronal metabolism in ALS are currently unknown, but the efficacy of dietary interventions shows promise for metabo...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Pharaoh, Gavin, Sataranatarajan, Kavithalakshmi, Street, Kaitlyn, Hill, Shauna, Gregston, Jake, Ahn, Bumsoo, Kinter, Caroline, Kinter, Michael, Van Remmen, Holly
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554287/
https://ncbi.nlm.nih.gov/pubmed/31213966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00487
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