Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia

Mice lacking the superoxide anion scavenger CuZn superoxide dismutase (Sod1(−/−) mice) develop a number of age-related phenotypes, including an early progression of muscle atrophy and weakness (sarcopenia) associated with loss of innervation. The purpose of this study was to delineate the early deve...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Sataranatarajan, Kavithalakshmi, Pharaoh, Gavin, Brown, Jacob L., Ranjit, Rojina, Piekarz, Katarzyna M., Street, Kaitlyn, Wren, Jonathan D., Georgescu, Constantin, Kinter, Caroline, Kinter, Michael, Freeman, Willard M., Richardson, Arlan, Van Remmen, Holly
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394980/
https://ncbi.nlm.nih.gov/pubmed/32394347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00189-x
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