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Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype
Our previous studies showed that adult (8 month) mice lacking CuZn-superoxide dismutase (CuZnSOD, Sod1KO mice) have neuromuscular changes resulting in dramatic accelerated muscle atrophy and weakness that mimics age-related sarcopenia. We have further shown that loss of CuZnSOD targeted to skeletal...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5022075/ https://ncbi.nlm.nih.gov/pubmed/25917273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.04.005 |
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