Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice

Deletion of copper-zinc superoxide dismutase (CuZnSOD) in Sod1(−/−) mice leads to accelerated loss of muscle mass and force during aging, but the losses do not occur with muscle-specific deletion of CuZnSOD. To determine the role of motor neurons in the muscle decline, we generated transgenic Sod1(−...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sakellariou, Giorgos K., Davis, Carol S., Shi, Yun, Ivannikov, Maxim V., Zhang, Yiqiang, Vasilaki, Aphrodite, Macleod, Gregory T., Richardson, Arlan, Van Remmen, Holly, Jackson, Malcolm J., McArdle, Anne, Brooks, Susan V.
פורמט: Artigo
שפה:Inglês
יצא לאור: Federation of American Societies for Experimental Biology 2014
נושאים:
Research Communications
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963022/
https://ncbi.nlm.nih.gov/pubmed/24378874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-240390
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים