Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice

Deletion of copper-zinc superoxide dismutase (CuZnSOD) in Sod1(−/−) mice leads to accelerated loss of muscle mass and force during aging, but the losses do not occur with muscle-specific deletion of CuZnSOD. To determine the role of motor neurons in the muscle decline, we generated transgenic Sod1(−...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sakellariou, Giorgos K., Davis, Carol S., Shi, Yun, Ivannikov, Maxim V., Zhang, Yiqiang, Vasilaki, Aphrodite, Macleod, Gregory T., Richardson, Arlan, Van Remmen, Holly, Jackson, Malcolm J., McArdle, Anne, Brooks, Susan V.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963022/
https://ncbi.nlm.nih.gov/pubmed/24378874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-240390
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados