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Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice
Deletion of copper-zinc superoxide dismutase (CuZnSOD) in Sod1(−/−) mice leads to accelerated loss of muscle mass and force during aging, but the losses do not occur with muscle-specific deletion of CuZnSOD. To determine the role of motor neurons in the muscle decline, we generated transgenic Sod1(−...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963022/ https://ncbi.nlm.nih.gov/pubmed/24378874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-240390 |
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