The Lack of CuZnSOD Leads to Impaired Neurotransmitter Release, Neuromuscular Junction Destabilization and Reduced Muscle Strength in Mice

Elevated reactive oxygen species (ROS) production and ROS-dependent protein damage is a common observation in the pathogenesis of many muscle wasting disorders, including sarcopenia. However, the contribution of elevated ROS levels to –a breakdown in neuromuscular communication and muscle atrophy re...

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Detalhes bibliográficos
Main Authors: Shi, Yun, Ivannikov, Maxim V., Walsh, Michael E., Liu, Yuhong, Zhang, Yiqiang, Jaramillo, Carlos A., Macleod, Gregory T., Van Remmen, Holly
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074103/
https://ncbi.nlm.nih.gov/pubmed/24971750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100834
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