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Misfolded CuZnSOD and amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive degenerative disease of motor neurons. The inherited form of the disease, familial ALS, represents 5–10% of the total cases, and the best documented of these are due to lesions in SOD1, the gene encoding copper–zinc superoxide dismutase (CuZnSOD)....
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152971/ https://ncbi.nlm.nih.gov/pubmed/12655070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730423100 |
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