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Misfolded CuZnSOD and amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive degenerative disease of motor neurons. The inherited form of the disease, familial ALS, represents 5–10% of the total cases, and the best documented of these are due to lesions in SOD1, the gene encoding copper–zinc superoxide dismutase (CuZnSOD)....

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Detalhes bibliográficos
Main Authors: Valentine, Joan Selverstone, Hart, P. John
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152971/
https://ncbi.nlm.nih.gov/pubmed/12655070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730423100
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