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Misfolded CuZnSOD and amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive degenerative disease of motor neurons. The inherited form of the disease, familial ALS, represents 5–10% of the total cases, and the best documented of these are due to lesions in SOD1, the gene encoding copper–zinc superoxide dismutase (CuZnSOD)....
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152971/ https://ncbi.nlm.nih.gov/pubmed/12655070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730423100 |
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