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Regulation of CuZnSOD and Its Redox Signaling Potential: Implications for Amyotrophic Lateral Sclerosis

Significance: Molecular oxygen is a Janus-faced electron acceptor for biological systems, serving as a reductant for respiration, or as the genesis for oxygen-derived free radicals that damage macromolecules. Superoxide is well known to perturb nonheme iron proteins, including Fe/S proteins such as...

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Autori principali: Hitchler, Michael J., Domann, Frederick E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960847/
https://ncbi.nlm.nih.gov/pubmed/23795822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5385
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