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Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice
Genetic ablation of CuZn-superoxide dismutase (Sod1) in mice (Sod1(−/−) mice) leads to shortened lifespan with a dramatic increase in hepatocellular carcinoma and accelerated aging phenotypes, including early onset sarcopenia. To study the tissue specific effects of oxidative stress in the Sod1(−/−)...
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| Publicado no: | Mech Ageing Dev |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855307/ https://ncbi.nlm.nih.gov/pubmed/26839948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.01.005 |
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