CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice

We have previously shown that deletion of CuZnSOD in mice (Sod1(−/−) mice) leads to accelerated loss of muscle mass and contractile force during aging. To dissect the relative roles of skeletal muscle and motor neurons in this process, we used a Cre-Lox targeted approach to establish a skeletal musc...

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Detalhes bibliográficos
Main Authors: Zhang, Yiqiang, Davis, Carol, Sakellariou, George K., Shi, Yun, Kayani, Anna C., Pulliam, Daniel, Bhattacharya, Arunabh, Richardson, Arlan, Jackson, Malcolm J., McArdle, Anne, Brooks, Susan V., Van Remmen, Holly
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752542/
https://ncbi.nlm.nih.gov/pubmed/23729587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-228130
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