Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD

Age-related loss of muscle mass and function, sarcopenia, has a major impact on the quality of life in the elderly. Among the proposed causes of sarcopenia are mitochondrial dysfunction and accumulated oxidative damage during aging. Dietary restriction (DR), a robust dietary intervention that extend...

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Detalhes bibliográficos
Main Authors: Jang, Young C., Liu, Yuhong, Hayworth, Christopher R., Bhattacharya, Arunabh, Lustgarten, Michael S., Muller, Florian L., Chaudhuri, Asish, Qi, Wenbo, Li, Yan, Huang, Jing-Yi, Verdin, Eric, Richardson, Arlan, Van Remmen, Holly
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444532/
https://ncbi.nlm.nih.gov/pubmed/22672615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00843.x
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