Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice

Age‐associated loss of muscle mass and function (sarcopenia) has a profound effect on the quality of life in the elderly. Our previous studies show that CuZnSOD deletion in mice (Sod1 (−/−) mice) recapitulates sarcopenia phenotypes, including elevated oxidative stress and accelerated muscle atrophy,...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Bhaskaran, Shylesh, Pollock, Natalie, C. Macpherson, Peter, Ahn, Bumsoo, Piekarz, Katarzyna M., Staunton, Caroline A., Brown, Jacob L., Qaisar, Rizwan, Vasilaki, Aphrodite, Richardson, Arlan, McArdle, Anne, Jackson, Malcolm J., Brooks, Susan V., Van Remmen, Holly
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576239/
https://ncbi.nlm.nih.gov/pubmed/32886862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13225
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