Tumor burden negatively impacts protein turnover as a proteostatic process in noncancerous liver, heart, and muscle, but not brain

av Brown, Jacob L., Lawrence, Marcus M., Borowik, Agnieszka, Oliver, Lauren, Peelor, Fredrick F., Van Remmen, Holly, Miller, Benjamin F.
I publikationen J Appl Physiol (1985) (2021)

Differential Effects of Leucine Supplementation in Young and Aged Mice at the Onset of Skeletal Muscle Regeneration

av Perry, Richard A., Brown, Lemuel A., Lee, David E., Brown, Jacob L., Baum, Jamie I., Greene, Nicholas P., Washington, Tyrone A.
I publikationen Mech Ageing Dev (2016)

The Akt/mTOR pathway: Data comparing young and aged mice with leucine supplementation at the onset of skeletal muscle regeneration

av Perry, Richard A., Brown, Lemuel A., Lee, David E., Brown, Jacob L., Baum, Jamie I., Greene, Nicholas P., Washington, Tyrone A.
I publikationen Data Brief (2016)

Mitochondrial Function and Protein Turnover in the Diaphragm are Altered in LLC Tumor Model of Cancer Cachexia

av Rosa-Caldwell, Megan E., Benson, Conner A., Lee, David E., Brown, Jacob L., Washington, Tyrone A., Greene, Nicholas P., Wiggs, Michael P.
I publikationen Int J Mol Sci (2020)

Mitochondrial quality control, promoted by PGC-1α, is dysregulated by Western diet-induced obesity and partially restored by moderate physical activity in mice

av Greene, Nicholas P, Lee, David E, Brown, Jacob L, Rosa, Megan E, Brown, Lemuel A, Perry, Richard A, Henry, Jordyn N, Washington, Tyrone A
I publikationen Physiol Rep (2015)

Cancer-induced Cardiac Atrophy Adversely Affects Myocardial Redox State and Mitochondrial Oxidative Characteristics

av Lee, David E., Brown, Jacob L., Rosa‐Caldwell, Megan E., Perry, Richard A., Brown, Lemuel A., Haynie, Wesley S., Washington, Tyrone A., Wiggs, Michael P., Rajaram, Narasimhan, Greene, Nicholas P.
I publikationen JCSM Rapid Commun (2020)

Hepatic alterations during the development and progression of cancer cachexia

av Rosa-Caldwell, Megan E., Brown, Jacob L., Lee, David E., Wiggs, Michael P., Perry, Richard A., Haynie, Wesley S., Caldwell, Aaron R., Washington, Tyrone A., Lo, Wen-Juo, Greene, Nicholas P.
I publikationen Appl Physiol Nutr Metab (2019)

Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia

av Sataranatarajan, Kavithalakshmi, Pharaoh, Gavin, Brown, Jacob L., Ranjit, Rojina, Piekarz, Katarzyna M., Street, Kaitlyn, Wren, Jonathan D., Georgescu, Constantin, Kinter, Caroline, Kinter, Michael, Freeman, Willard M., Richardson, Arlan, Van Remmen, Holly
I publikationen GeroScience (2020)

Targeting cPLA(2) derived lipid hydroperoxides as a potential intervention for sarcopenia

av Pharaoh, Gavin, Brown, Jacob L., Sataranatarajan, Kavithalakshmi, Kneis, Parker, Bian, Jan, Ranjit, Rojina, Hadad, Niran, Georgescu, Constantin, Rabinovitch, Peter, Ran, Qitao, Wren, Jonathan D., Freeman, Willard, Kinter, Michael, Richardson, Arlan, Van Remmen, Holly
I publikationen Sci Rep (2020)

Female mice may have exacerbated catabolic signalling response compared to male mice during development and progression of disuse atrophy

av Rosa‐Caldwell, Megan E., Lim, Seongkyun, Haynie, Wesley A., Brown, Jacob L., Deaver, John William, Morena Da Silva, Francielly, Jansen, Lisa T., Lee, David E., Wiggs, Michael P., Washington, Tyrone A., Greene, Nicholas P.
I publikationen J Cachexia Sarcopenia Muscle (2021)

Protein imbalance in the development of skeletal muscle wasting in tumour‐bearing mice

av Brown, Jacob L., Lee, David E., Rosa‐Caldwell, Megan E., Brown, Lemuel A., Perry, Richard A., Haynie, Wesley S., Huseman, Kendra, Sataranatarajan, Kavithalakshmi, Van Remmen, Holly, Washington, Tyrone A., Wiggs, Michael P., Greene, Nicholas P.
I publikationen J Cachexia Sarcopenia Muscle (2018)

Regulation of mitochondrial quality following repeated bouts of hindlimb unloading

av Rosa-Caldwell, Megan E., Brown, Jacob L., Perry, Richard A., Shimkus, Kevin L., Shirazi-Fard, Yasaman, Brown, Lemuel A., Hogan, Harry A., Fluckey, James D., Washington, Tyrone A., Wiggs, Michael P., Greene, Nicholas P.
I publikationen Appl Physiol Nutr Metab (2019)

Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour‐bearing mice

av Brown, Jacob L., Rosa‐Caldwell, Megan E., Lee, David E., Blackwell, Thomas A., Brown, Lemuel A., Perry, Richard A., Haynie, Wesley S., Hardee, Justin P., Carson, James A., Wiggs, Michael P., Washington, Tyrone A., Greene, Nicholas P.
I publikationen J Cachexia Sarcopenia Muscle (2017)

Neuron‐specific deletion of CuZnSOD leads to an advanced sarcopenic phenotype in older mice

av Bhaskaran, Shylesh, Pollock, Natalie, C. Macpherson, Peter, Ahn, Bumsoo, Piekarz, Katarzyna M., Staunton, Caroline A., Brown, Jacob L., Qaisar, Rizwan, Vasilaki, Aphrodite, Richardson, Arlan, McArdle, Anne, Jackson, Malcolm J., Brooks, Susan V., Van Remmen, Holly
I publikationen Aging Cell (2020)

Cancer cachexia in a mouse model of oxidative stress

av Brown, Jacob L., Lawrence, Marcus M., Ahn, Bumsoo, Kneis, Parker, Piekarz, Katarzyna M., Qaisar, Rizwan, Ranjit, Rojina, Bian, Jan, Pharaoh, Gavin, Brown, Chase, Peelor, Fredrick F., Kinter, Michael T., Miller, Benjamin F., Richardson, Arlan, Van Remmen, Holly
I publikationen J Cachexia Sarcopenia Muscle (2020)

Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing mice

av Blackwell, Thomas A., Cervenka, Igor, Khatri, Bhuwan, Brown, Jacob L., Rosa-Caldwell, Megan E., Lee, David E., Perry, Richard A., Brown, Lemuel A., Haynie, Wesley S., Wiggs, Michael P., Bottje, Walter G., Washington, Tyrone A., Kong, Byungwhi C., Ruas, Jorge L., Greene, Nicholas P.
I publikationen Physiol Genomics (2018)