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Transgenic expression of SOD1 specifically in neurons of Sod1 deficient mice prevents defects in muscle mitochondrial function and calcium handling
Aging is accompanied by loss of muscle mass and force, known as sarcopenia. Muscle atrophy, weakness, and neuromuscular junction (NMJ) degeneration reminiscent of normal muscle aging are observed early in adulthood for mice deficient in Cu, Zn-superoxide dismutase (SOD, Sod1(−/−)). Muscles of Sod1(−...
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| Publicado no: | Free Radic Biol Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026109/ https://ncbi.nlm.nih.gov/pubmed/33561489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2021.01.047 |
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