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Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors
Methyltransferases (MTases) play diverse roles in cellular processes. Aberrant methylation levels have been implicated in many diseases, indicating the need for the identification and development of small molecule inhibitors for each MTase. Specific inhibitors can serve as probes to investigate the...
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| Udgivet i: | ACS Comb Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429283/ https://ncbi.nlm.nih.gov/pubmed/32525297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.0c00077 |
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