Cell Lysate-Based AlphaLISA Deubiquitinase Assay Platform for Identification of Small Molecule Inhibitors

The deubiquitinases, or DUBs, are associated with various human diseases, including neurological disorders, cancer, and viral infection, making them excellent candidates for pharmacological intervention. Drug discovery campaigns against DUBs require enzymatic deubiquitination assays amenable for hig...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Ott, Christine A, Baljinnyam, Bolormaa, Zakharov, Alexey V., Jadhav, Ajit, Simeonov, Anton, Zhuang, Zhihao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947317/
https://ncbi.nlm.nih.gov/pubmed/28836754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00543
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