Wird geladen...

PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression

Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC) initiation and progression. However, the mechanisms that regulate autophagy and metabolic reprogramming during reactive oxygen species (ROS) generation, and how ROS promote tumorigenesis, still need t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer Cell
Hauptverfasser: Kudo, Yotaro, Sugimoto, Masayuki, Arias, Esperanza, Kasashima, Hiroaki, Cordes, Thekla, Linares, Juan F., Duran, Angeles, Nakanishi, Yuki, Nakanishi, Naoko, L’Hermitte, Antoine, Campos, Alex, Senni, Nadia, Rooslid, Tarmo, Roberts, Lewis R., Maria Cuervo, Ana, Metallo, Christian M., Karin, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423690/
https://ncbi.nlm.nih.gov/pubmed/32589943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.05.018
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!