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PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression
Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC) initiation and progression. However, the mechanisms that regulate autophagy and metabolic reprogramming during reactive oxygen species (ROS) generation, and how ROS promote tumorigenesis, still need t...
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| izdano v: | Cancer Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7423690/ https://ncbi.nlm.nih.gov/pubmed/32589943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.05.018 |
| Oznake: |
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