PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression

Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC) initiation and progression. However, the mechanisms that regulate autophagy and metabolic reprogramming during reactive oxygen species (ROS) generation, and how ROS promote tumorigenesis, still need t...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cancer Cell
Main Authors: Kudo, Yotaro, Sugimoto, Masayuki, Arias, Esperanza, Kasashima, Hiroaki, Cordes, Thekla, Linares, Juan F., Duran, Angeles, Nakanishi, Yuki, Nakanishi, Naoko, L’Hermitte, Antoine, Campos, Alex, Senni, Nadia, Rooslid, Tarmo, Roberts, Lewis R., Maria Cuervo, Ana, Metallo, Christian M., Karin, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423690/
https://ncbi.nlm.nih.gov/pubmed/32589943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.05.018
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares