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Regulation of Asymmetric Division and CD8(+) T Lymphocyte Fate Specification by PKCζ and PKCλ/ι

During an immune response against a microbial pathogen, activated naïve T lymphocytes give rise to effector cells that provide acute host defense and memory cells that provide long-lived immunity. It has been shown that T lymphocytes can undergo asymmetric division, enabling the daughter cells to in...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Metz, Patrick J., Arsenio, Janilyn, Kakaradov, Boyko, Kim, Stephanie H., Remedios, Kelly A., Oakley, Katherine, Akimoto, Kazunori, Ohno, Shigeo, Yeo, Gene W., Chang, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340726/
https://ncbi.nlm.nih.gov/pubmed/25617472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401652
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