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Early specification of CD8(+) T lymphocyte fates during adaptive immunity revealed by single-cell gene expression analyses
T lymphocytes responding to microbial infection give rise to effector cells that mediate acute host defense and memory cells that provide long-lived immunity, but the fundamental question of when and how these cells arise remains unresolved. Here we combine single-cell gene expression analyses with...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968536/ https://ncbi.nlm.nih.gov/pubmed/24584088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2842 |
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