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Early specification of CD8(+) T lymphocyte fates during adaptive immunity revealed by single-cell gene expression analyses

T lymphocytes responding to microbial infection give rise to effector cells that mediate acute host defense and memory cells that provide long-lived immunity, but the fundamental question of when and how these cells arise remains unresolved. Here we combine single-cell gene expression analyses with...

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Hlavní autoři: Arsenio, Janilyn, Kakaradov, Boyko, Metz, Patrick J., Kim, Stephanie H., Yeo, Gene W., Chang, John T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968536/
https://ncbi.nlm.nih.gov/pubmed/24584088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2842
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