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Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates

Naïve CD8(+) T lymphocytes responding to microbial pathogens give rise to effector T cells that provide acute defense and memory T cells that provide long-lived immunity. Upon activation, CD8(+) T lymphocytes can undergo asymmetric division, unequally distributing factors to the nascent daughter cel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Metz, Patrick J., Lopez, Justine, Kim, Stephanie H., Akimoto, Kazunori, Ohno, Shigeo, Chang, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725917/
https://ncbi.nlm.nih.gov/pubmed/26765121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19182
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