Proteasome activity regulates CD8(+) T lymphocyte metabolism and fate specification

During an immune response, CD8(+) T lymphocytes can undergo asymmetric division, giving rise to daughter cells that exhibit distinct tendencies to adopt terminal effector and memory cell fates. Here we show that “pre-effector” and “pre-memory” cells resulting from the first CD8(+) T cell division in...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Widjaja, Christella E., Olvera, Jocelyn G., Metz, Patrick J., Phan, Anthony T., Savas, Jeffrey N., de Bruin, Gerjan, Leestemaker, Yves, Berkers, Celia R., de Jong, Annemieke, Florea, Bogdan I., Fisch, Kathleen, Lopez, Justine, Kim, Stephanie H., Garcia, Daniel A., Searles, Stephen, Bui, Jack D., Chang, Aaron N., Yates, John R., Goldrath, Ananda W., Overkleeft, Hermen S., Ovaa, Huib, Chang, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617668/
https://ncbi.nlm.nih.gov/pubmed/28846070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90895
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