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Control of Paneth cell fate, intestinal inflammation and tumorigenesis by PKCλ/ι
Paneth cells are a highly specialized population of intestinal epithelial cells located in the crypt adjacent to Lgr5(+) stem cells, from which they differentiate through a process that requires downregulation of the Notch pathway. Their ability to store and release antimicrobial peptides protects t...
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| Published in: | Cell Rep |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5043519/ https://ncbi.nlm.nih.gov/pubmed/27653691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.054 |
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