Control of Paneth cell fate, intestinal inflammation and tumorigenesis by PKCλ/ι

Paneth cells are a highly specialized population of intestinal epithelial cells located in the crypt adjacent to Lgr5(+) stem cells, from which they differentiate through a process that requires downregulation of the Notch pathway. Their ability to store and release antimicrobial peptides protects t...

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Vydáno v:Cell Rep
Hlavní autoři: Nakanishi, Yuki, Reina-Campos, Miguel, Nakanishi, Naoko, Llado, Victoria, Elmen, Lisa, Peterson, Scott, Campos, Alex, De, Surya K., Leitges, Michael, Ikeuchi, Hiroki, Pellecchia, Maurizio, Blumberg, Richard S., Diaz-Meco, Maria T., Moscat, Jorge
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043519/
https://ncbi.nlm.nih.gov/pubmed/27653691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.054
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