PKCλ/ι loss induces autophagy, oxidative phosphorylation, and NRF2 to promote liver cancer progression

Oxidative stress plays a critical role in liver tissue damage and in hepatocellular carcinoma (HCC) initiation and progression. However, the mechanisms that regulate autophagy and metabolic reprogramming during reactive oxygen species (ROS) generation, and how ROS promote tumorigenesis, still need t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Cell
Egile Nagusiak: Kudo, Yotaro, Sugimoto, Masayuki, Arias, Esperanza, Kasashima, Hiroaki, Cordes, Thekla, Linares, Juan F., Duran, Angeles, Nakanishi, Yuki, Nakanishi, Naoko, L’Hermitte, Antoine, Campos, Alex, Senni, Nadia, Rooslid, Tarmo, Roberts, Lewis R., Maria Cuervo, Ana, Metallo, Christian M., Karin, Michael, Diaz-Meco, Maria T., Moscat, Jorge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423690/
https://ncbi.nlm.nih.gov/pubmed/32589943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.05.018
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